WALTER LINCOLN PALMER, M.D.
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The purpose of this paper is to consider briefly the relationship between benign and malignant gastric ulcers, the clinical differentiation of the two lesions, and the therapeutic implications.
A few years after Cruveilhier differentiated gastric ulcer from gastric carcinoma, Rokitansky described a case interpreted as showing the carcinomatous transformation of a benign ulcer. An enormous controversial literature has since developed regarding, first, the existence of carcinomatous degeneration in ulcer, and, secondly, the incidence of such a process. A critical review of the subject has led me to doubt the existence of such a transformation. The alleged evidence for such
PALMER WL. BENIGN AND MALIGNANT GASTRIC ULCERS: THEIR RELATION AND CLINICAL DIFFERENTIATION1. Ann Intern Med. ;13:317–338. doi: 10.7326/0003-4819-13-2-317
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Published: Ann Intern Med. 1939;13(2):317-338.
Gastroenterology/Hepatology, Peptic Disease, Peptic Ulcer.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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