HAROLD W. PALMER, M.D., F.A.C.P.
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In 1911, in his original monograph, Günther1 described a rare constitutional disturbance which he called hematoporphyria, the essential symptom of which was the finding of large quantities of hematoporphyrin in the urine. He later made the statement, confirmed by Hoppe-Seyler, that hematoporphyrin was not the pigment found in the urine in this disease, but that the pigments actually were copraporphyrin and uroporphyrin, related substances. However, through general acceptance by Garrod and others, the pigment is still referred to as hematoporphyrin and the disease state as hematoporphyria. In 1925 Günther1 attempted to classify the hematoporphyria into three separate groups, namely, (1)
PALMER HW. A CASE OF ACUTE IDIOPATHIC HEMATOPORPHYRIA WITH ACUTE ASCENDING PARALYSIS1. Ann Intern Med. ;13:1500–1508. doi: 10.7326/0003-4819-13-8-1500
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Published: Ann Intern Med. 1940;13(8):1500-1508.
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