CHARLES F. NICHOLS, M.D., F.A.C.P.
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The widespread interest now manifested in the early diagnosis and adequate treatment of syphilis would seem to justify once again a review of the tragic effects of this disease on the cardiovascular system. The term "cardiovascular syphilis" is widely used but, in order properly to understand the evolution of the disease, the term "vascular syphilis" would be preferable. Excepting only cerebral vascular syphilis and rare involvement of other vessels (as the innominate artery), vascular syphilis in the great majority of cases resolves itself into syphilis of the aorta. Primary involvement of the aortic valves and heart, although it does occur,
NICHOLS CF. A STUDY OF SYPHILIS OF THE AORTA AND AORTIC VALVE AREA1. Ann Intern Med. 1940;14:960–977. doi: 10.7326/0003-4819-14-6-960
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Published: Ann Intern Med. 1940;14(6):960-977.
Cardiology, Infectious Disease, Sexually Transmitted Infections, Valvular Heart Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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