H. J. SCHATTENBERG, M.S., M.D.; JOHN F. RYAN, A.B., M.D.
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Infiltration of the pleural, peribronchial, and perivascular lymphatics by neoplastic cells is a condition first noted by Andral1 in 1829, again by Virchow2 in 1855 and of which the gross lesions and the histopathology were described in detail by Troissier3 and Raynaud4 in 1874. It is most commonly secondary to carcinoma of the stomach, usually of the scirrhous infiltrating type, but primary sites in the bronchus and breast,5 rectum,6 kidney,7, 8 ovary,9 tongue,10 prostate11 and liver,12 have been noted. The primary gastric malignancy is often clinically latent, or causes few symptoms, and the presenting complaints are those of respiratory or
SCHATTENBERG HJ, RYAN JF. LYMPHANGITIC CARCINOMATOSIS OF THE LUNGS; CASE REPORT WITH AUTOPSY FINDINGS1. Ann Intern Med. 1941;14:1710–1721. doi: 10.7326/0003-4819-14-9-1710
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Published: Ann Intern Med. 1941;14(9):1710-1721.
Hematology/Oncology, Lung Cancer, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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