WILLIS M. FOWLER, M.D.
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Hemolytic icterus, in its literal sense, is a term so broad and inclusive that it may embrace a wide variety of conditions in which there is hemolysis of the erythrocytes and anemia. By common usage the term is applied to a more specific entity characterized not only by increased hemolysis and anemia, but by splenomegaly, increased fragility of the erythrocytes and evidences of bone marrow stimulation. This disease has been subdivided into the familial or congenital (Chauffard-Minkowski) type and the acquired (Hayem-Widal) type. The former represents a definite, clear-cut, clinical entity, whereas there is a diversity of opinion as to
FOWLER WM. ACQUIRED HEMOLYTIC ICTERUS1. Ann Intern Med. ;14:1838–1848. doi: 10.7326/0003-4819-14-10-1838
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Published: Ann Intern Med. 1941;14(10):1838-1848.
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