JOHN G. GIBSON 2nd, M.D.
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The total quantity of circulating blood in normal humans and the nature and magnitude of the changes incident to disease have long been of interest to practitioners, but in the main these questions have remained a puzzle. Interest has waxed as new methods have been introduced and waned as they were found wanting. A review of methods extant is not intended. The dye injection method devised by Keith, Rowntree and Geraghty1 in 1915 has been the most widely used of any, yet the numerous modifications of the original technic that have appeared2, 3, 4, 5, 6, 7, 8, 9, 10,
GIBSON JG. THE CLINICAL SIGNIFICANCE OF THE BLOOD VOLUME1. Ann Intern Med. 1941;14:2014–2026. doi: 10.7326/0003-4819-14-11-2014
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Published: Ann Intern Med. 1941;14(11):2014-2026.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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