C. J. SMYTH, M.D.; R. H. FREYBERG, M.D.
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Stimulated by the observation of gout in several members of one family we have made a systematic study of all of the immediate relatives of two gouty individuals in order to determine the importance of heredity as a factor in the etiology of this disease. In the vast amount of literature on the subject of gout and uric acid, reports of proved cases of gout in near relatives of patients in whom the diagnosis of gout has been established are sufficiently rare to make this study valuable. As far as can be determined, this is the first systematic investigation of
SMYTH CJ, FREYBERG RH. A STUDY OF THE HEREDITARY NATURE OF GOUT; A REPORT OF TWO FAMILIES1. Ann Intern Med. 1942;16:46–56. doi: 10.7326/0003-4819-16-1-46
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Published: Ann Intern Med. 1942;16(1):46-56.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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