RENO R. PORTER, M.D.; ROGER S. DOWNS, M.D.
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Observations on the cardiovascular disturbances accompanying vitamin B1 deficiency in man have accumulated rapidly during the past decade. Aalsmeer and Wenckebach1 and Keefer7 described the cardiac form of beriberi occurring in the Orient. Scott and Herrmann12 found similar cases of cardiac failure among the rice cultivators of Louisiana who developed the "maladie des jambes" each autumn when the diet consisted of polished rice and bacon grease.
Minot, Strauss and Cobb9 recognized the importance of nutritional deficiency and especially deficiency of vitamin B1 in the etiology of "alcoholic" polyneuritis and compared this condition to beriberi. A few years later Weiss and
PORTER RR, DOWNS RS. SOME PHYSIOLOGICAL OBSERVATIONS ON THE CIRCULATION DURING RECOVERY FROM VITAMIN B1 DEFICIENCY1. Ann Intern Med. ;17:645–658. doi: 10.7326/0003-4819-17-4-645
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Published: Ann Intern Med. 1942;17(4):645-658.
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