JAMES F. RINEHART, M.D.; LOUIS D. GREENBERG, PH.D.
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Clinically classical scurvy is uncommon although cases are still encountered occasionally in infants and less frequently in adults. Is there a lesser degree of vitamin C deficiency which undermines health but is not manifest as scurvy? Nutrition is one factor over which we have some control. Optimal health is, of course, the goal of medicine and it assumes particular importance in times of national stress. If the vitamin C nutrition is suboptimal in any considerable portion of our population it is important that we should know it and define methods for its recognition.
Considered from a biochemical standpoint there is
RINEHART JF, GREENBERG LD. THE DETECTION OF SUBCLINICAL SCURVY OR VITAMIN C DEFICIENCY1. Ann Intern Med. 1942;17:672–680. doi: 10.7326/0003-4819-17-4-672
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Published: Ann Intern Med. 1942;17(4):672-680.
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