J. S. BROWNING, M.D.
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This case is being reported because of the apparent rarity of the condition and the fairly typical clinical course exhibited. A review of the literature up to the time this paper was written revealed only 131 similar cases reported in man, seven of which had either lymph node or liver metastasis or both. This patient presented the usual clinical picture associated with hyperinsulinism.2 It is to be regretted that a biological assay for insulin was not made of the metastatic nodules in the liver, as has been shown by Powers and Wilder to be conclusive proof of the origin of
BROWNING JS. CARCINOMA OF THE ISLANDS OF LANGERHANS WITH LIVER METASTASIS PRODUCING HYPERINSULINISM*. Ann Intern Med. 1943;19:669–673. doi: https://doi.org/10.7326/0003-4819-19-4-669
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Published: Ann Intern Med. 1943;19(4):669-673.
Gastroenterology/Hepatology, Gastrointestinal Cancer, Hematology/Oncology, Liver Cancer, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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