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Toxoplasma is an intracellular parasite, usually regarded as a protozoan, which has been found in many species of birds and mammals, particularly rodents. It was first described by Nicolle and Manceaux (1908) in a North African rodent, the gundi. Although there are several early descriptions of morphologically similar organisms in human cases, the identification of the organism was questionable, and at best such cases were regarded as clinical curiosities. In 1939, however, Wolf, Cowen and Paige1 brought convincing proof of Toxoplasma infection in an infant dying of encephalomyelitis. Since then evidence has been accumulating that human infection is by no
TOXOPLASMA INFECTION IN MAN. Ann Intern Med. ;20:832–836. doi: 10.7326/0003-4819-20-5-832
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Published: Ann Intern Med. 1944;20(5):832-836.
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