FREDRICK F. YONKMAN, M.D.; PAUL H. NOTH, M.D., M.S.; HANS H. HECHT, M.D.
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The disadvantages attending therapeutic use of morphine and other analgetics have impelled investigators in numerous fields of medical endeavor to seek an adequate substitute for the relief of pain. Codeine, dilaudid, snake venom and other agents recently introduced do not subscribe in every respect to the specification of 'adequate substitute' because of various side-effects or other disadvantages associated with each. However, a synthetic substance which in some respects equals or surpasses morphine is available in demerol. It appears in the literature under various names such as Dolantin, Dolantol, D-140, S-140, and more recently as Demerol, which is the most generally
YONKMAN FF, NOTH PH, HECHT HH. DEMEROL: A NEW SYNTHETIC ANALGETIC, SPASMOLYTIC AND SEDATIVE AGENT. I. PHARMACOLOGIC STUDIES*. Ann Intern Med. 1944;21:7–16. doi: https://doi.org/10.7326/0003-4819-21-1-7
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Published: Ann Intern Med. 1944;21(1):7-16.
Hospital Medicine, Infectious Disease, Pneumonia, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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