PAUL H. NOTH, M.D., M.S. (in Medicine); HANS H. HECHT, M.D.; FREDERICK F. YONKMAN, M.D., PH.D.
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The chemical composition and pharmacologic properties of demerol have been described in a separate communication.1 The present report deals with clinical observations of the actions of this drug. Since 1939 a great number of clinical reports on demerol (variously called Dolantin, Dolantol, Alba, D-140, S-140) have appeared in the South American and European literature including observations on more than 2,000 cases. Only a few clinical studies, however, have been published in this country,2, 3, 4, 5, 6, 7 including a series of papers by Himmelsbach and Andrews on tolerance and addiction liabilities in former morphine addicts.8, 9, 10 We have
NOTH PH, HECHT HH, YONKMAN FF. DEMEROL: A NEW SYNTHETIC ANALGETIC, SPASMOLYTIC, AND SEDATIVE AGENT. II. CLINICAL OBSERVATIONS*. Ann Intern Med. 1944;21:17–34. doi: https://doi.org/10.7326/0003-4819-21-1-17
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Published: Ann Intern Med. 1944;21(1):17-34.
Hospital Medicine, Infectious Disease, Pneumonia, Pulmonary/Critical Care.
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