ELMER C. BARTELS, M.D., F.A.C.P.
A preliminary report on the use of thiouracil in the preoperative management of 12 toxic hyperthyroid patients at the Lahey Clinic was published in May 1944.1 We were convinced of the effectiveness of this drug and since then we have continued to use thiouracil as a preoperative therapeutic agent in a total of 64 patients. The patients treated were severely toxic and would have incurred more than the average surgical risk if they had been prepared in the usual manner by administration of Lugol's solution. Most of these patients would have required multiple stage operations, but with thiouracil most went
BARTELS EC. USE OF THIOURACIL IN THE PREOPERATIVE PREPARATION OF PATIENTS WITH SEVERE HYPERTHYROIDISM*. Ann Intern Med. 1945;22:365–372. doi: https://doi.org/10.7326/0003-4819-22-3-365
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Published: Ann Intern Med. 1945;22(3):365-372.
DOI: 10.7326/0003-4819-22-3-365
Endocrine and Metabolism, Thyroid Disorders.
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