J. H. MEANS, M.D., F.A.C.P.
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My first job obviously must be to define, and defend, the somewhat monstrous title of my paper. The point is that an all inclusive term is needed to cover a spectrum of clinical pictures, probably of the same or similar etiology, which shade one into another. I have used the term Graves' disease for this purpose. Toxic goiter will not do because all the cases in the group are not toxic, nor do they all have goiters. Nor will exophthalmic goiter fill the bill for exophthalmos and related eye signs may be lacking.
Since the etiology of this disturbance is
MEANS JH. HYPEROPHTHALMOPATHIC GRAVES' DISEASE1. Ann Intern Med. ;23:779–789. doi: 10.7326/0003-4819-23-5-779
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Published: Ann Intern Med. 1945;23(5):779-789.
Endocrine and Metabolism, Thyroid Disorders.
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