EMANUEL M. RAPPAPORT
There are few problems confronting the internist more challenging, vexing and yet intriguing than fever which persists for weeks or months without yielding a single clue as to its origin. Not infrequently, time or the laboratory establishes the diagnosis. With the elapse of a sufficient period of observation, some leading symptom or clinical finding becomes manifest or one of the usually numerous laboratory tests enlisted in the search yields the clue to solution.
The upper limit of normal oral temperature is almost universally regarded as 99° F. with rectal temperature one-half to three-quarters degree higher. Wright1 accepts the range as
RAPPAPORT EM. ESSENTIAL ORAL HYPERTHERMIA; REPORT OF A STUDY OF 25 CASES OF LOW GRADE 'FEVER'*. Ann Intern Med. 1946;25:1–14. doi: https://doi.org/10.7326/0003-4819-25-1-1
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Published: Ann Intern Med. 1946;25(1):1-14.
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