WALTER L. BLOOM; DAVID SEEGAL
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The term "nephrotic phase" is used to describe a syndrome occurring during the course of chronic glomerulonephritis and characterized by albuminuria, hypoproteinemia, hypercholesterolemia and edema. In general, these features have served as the criteria for diagnosis.1, 2 The degrees of hypoproteinemia, proteinuria, edema and lipemia necessary for the diagnosis have not been clearly defined.
There is agreement over the occurrence of the nephrotic phase in particular types of renal diseases which terminate in renal failure. Baehr3 noted that "every case of glomerulonephritis has a nephrotic element." Christian4 agrees with this opinion. The rarity of the nephrotic phase in arteriolarnephrosclerosis
BLOOM WL, SEEGAL D. THE NEPHROTIC PHASE: ITS FREQUENCY OF OCCURRENCE AND ITS DIFFERENTIAL DIAGNOSTIC VALUE IN DETERMINING THE NATURE OF THE RENAL LESION IN 120 PATIENTS WHO DIED OF RENAL FAILURE*. Ann Intern Med. 1946;25:15–21. doi: https://doi.org/10.7326/0003-4819-25-1-15
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Published: Ann Intern Med. 1946;25(1):15-21.
Nephrology, Nephrotic Syndrome.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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