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This monograph is based on a three year study of hepatic changes noted in hyperthyroidism. The literature is thoroughly reviewed and the bibliography complete. The author is not impressed by jaundice, reported by others as a common feature in thyrohepatic disturbances. The Quick hippuric acid synthesis test and the Bauer galactose tolerance test uniformly indicated liver cell function disturbance. Thus the mechanisms disturbed were the "antitoxic" and glycogen storage.
A correlation between the thyroid and liver is generally recognized, but no signal evidence of this relationship outside of jaundice which occurs uncommonly is identifiable in the clinical picture of hyperthyroidism.
Alteracões Hepáticas na Tireotoxicose.. Ann Intern Med. 1946;25:542. doi: https://doi.org/10.7326/0003-4819-25-3-542
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Published: Ann Intern Med. 1946;25(3):542.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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