E. B. ASTWOOD; W. P. VANDERLAAN
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The current differences of opinion regarding the best form of treatment for hyperthyroidism are a reflection of the fact that of the several effective methods which are available, none is devoid of significant disadvantages. Experience with the use of antithyroid compounds is sufficient to show that this is a highly effective form of treatment, but extensive clinical trials have been carried out only with one such drug, thiouracil. The disadvantage attending the use of this compound relates almost exclusively to its side effects,1 the drug fever syndrome or some variant of it and agranulocytosis. The former reaction usually precludes the
ASTWOOD EB, VANDERLAAN WP. TREATMENT OF HYPERTHYROIDISM WITH PROPYLTHIOURACIL*. Ann Intern Med. 1946;25:813–821. doi: https://doi.org/10.7326/0003-4819-25-5-813
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Published: Ann Intern Med. 1946;25(5):813-821.
Endocrine and Metabolism, Thyroid Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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