JOHN B. JOHNSON, M.D.; EDWARD C. MAZIQUE, M.D.
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Disseminate lupus erythematosus is a systemic disease which may be acute, subacute or chronic. Manifestations are commonly found in the skin, joints and viscera. Sixty to 80 per cent of the cases of the disseminate form occur in females during the second and third decades of life.1 The mortality rate in the subacute form is about 50 per cent, whereas in the acute form it is reported as invariably fatal.2 The etiology and pathogenesis of this disorder are still unknown. Stokes and associates3 have attempted to integrate the variegated manifestation of lupus erythematosus on an infection-allergy basis with major involvement
JOHNSON JB, MAZIQUE EC. DISSEMINATE LUPUS ERYTHEMATOSUS UNSUCCESSFULLY TREATED WITH PENICILLIN, ROENTGEN-RAY CASTRATION AND SERUM ALBUMIN1. Ann Intern Med. 1946;25:859–862. doi: 10.7326/0003-4819-25-5-859
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Published: Ann Intern Med. 1946;25(5):859-862.
Lupus Erythematosus, Rheumatology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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