ALVIN H. HONIGMAN, M.D.; JAMES R. KARNS, M.D.
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Even though reported clinical cures of subacute bacterial endocarditis have become more frequent, there is still a remarkable paucity of pathologic confirmation of healed subacute endocarditis.
Before the advent of penicillin, Weiss and Rhodes,1 Libman,2 and Hamman3 reported autopsied cases in which the heart lesions gave evidence of complete healing. Since penicillin has been added to the armamentarium there have been increasing opportunities to study cardiac specimens of patients dying after apparently successful treatment. A very high percentage of these patients had succumbed as a result of cardiac complications. In this group Rosenblatt and Loewe4 included two of their cases
HONIGMAN AH, KARNS JR. HEALED SUBACUTE BACTERIAL ENDOCARDITIS: REPORT OF TWO CASES WITH DEATH DUE TO CONGESTIVE HEART FAILURE1. Ann Intern Med. 1947;26:704–712. doi: 10.7326/0003-4819-26-5-704
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Published: Ann Intern Med. 1947;26(5):704-712.
Cardiology, Endocarditis, Heart Failure, Infectious Disease, Streptococcal Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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