LEWIS B. FLINN, M.D., F.A.C.P.; EDWARD MINNICK, M.D.; DOUGLAS M. GAY, M.D.
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Organic hyperinsulinism has been recognized with increasing frequency in the last few years. It is most commonly due to adenomata of the islands of Langerhans. More and more case reports appear of successful surgical removal of these tumors with consequent alleviation of symptoms. At times there seems to be a general hypersecretion of insulin by the islet cells without discernible tumor in which resection of varying amounts of pancreatic tissue has been found effective. Carcinoma of islet cells occurs much less frequently. In these cases the tumor is often slow to grow and slow to metastasize. In a few instances
FLINN LB, MINNICK E, GAY DM. ALLOXAN IN THE TREATMENT OF A CASE OF ISLET CELL CARCINOMA OF THE PANCREAS WITH LIVER METASTASES1. Ann Intern Med. ;26:936–945. doi: 10.7326/0003-4819-26-6-936
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Published: Ann Intern Med. 1947;26(6):936-945.
Gastroenterology/Hepatology, Gastrointestinal Cancer, Hematology/Oncology, Liver Cancer, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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