GUY A. CALDWELL, M.D.; T. F. BRODERICK JR., M.D.
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Interest in cystic lesions of bone was greatly stimulated by the successful removal of a parathyroid adenoma by Mandl1 in 1925. Since that time generalized osteitis fibrosa cystica of von Recklinghausen has been recognized as due to adenoma or hypertrophy of the parathyroid glands. However, the occurrence of other cystic bone lesions, either generalized or localized, without obvious abnormality of calcium and phosphorus metabolism, has been noted with increasing frequency and has aroused considerable speculation as to the nature of this condition or variety of conditions.
In 1937 Albright, Butler, Hampton and Smith2 called attention to a syndrome characterized
CALDWELL GA, BRODERICK TF. POLYOSTOTIC FIBROUS DYSPLASIA IN ONE OF NEGRO TWIN GIRLS1. Ann Intern Med. 1947;27:114–126. doi: 10.7326/0003-4819-27-1-114
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Published: Ann Intern Med. 1947;27(1):114-126.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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