W. BARRY WOOD JR., F.A.C.P.
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Although the treatment of acute bacterial pneumonia has been revolutionized in recent years by the advent of chemotherapy, the exact mechanism of recovery is not known. Pertinent to the problem are the following basic facts:
1. Most of the bacteria that cause the more common forms of acute pneumonia are encapsulated (pneumococcus, beta hemolytic streptococcus, Friedländer's bacillus, influenza bacillus, staphylococcus), and the presence of the capsules renders the organisms resistant to phagocytosis.1 According to present concepts of immunology, fully encapsulated microörganisms can be phagocyted only in the presence of suitable opsonins.2
2. Sulfonamide drugs that are highly effective in the
WOOD WB. THE MECHANISM OF RECOVERY IN ACUTE BACTERIAL PNEUMONIA1. Ann Intern Med. ;27:347–352. doi: 10.7326/0003-4819-27-3-347
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Published: Ann Intern Med. 1947;27(3):347-352.
Infectious Disease, Pneumonia, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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