GEORGE HOLLANDER, M.D.; HARRY MANDELBAUM, M.D., F.A.C.P.
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Effective and striking results in the treatment of angina pectoris have been obtained with total thyroidectomy.1, 2 Its shortcomings—the risk of surgery, subsequent complications and irreparable loss of thyroid function—have limited its use to patients with a fair life expectancy who are adequate surgical risks. At the present time, drugs which selectively act to block the formation of active thyroid hormone to give rise to a reversible, chemical thyroidectomy, include radioactive iodine and the thiouracil group. In many, these are a medical substitute for surgery, without its discomfort and occasional mortality. The newer, more powerful and less toxic derivatives of
HOLLANDER G, MANDELBAUM H. THE TREATMENT OF ANGINA PECTORIS WITH PROPYLTHIOURACIL*. Ann Intern Med. 1948;28:1150–1156. doi: https://doi.org/10.7326/0003-4819-28-6-1150
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Published: Ann Intern Med. 1948;28(6):1150-1156.
Cardiology, Coronary Heart Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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