PAUL M. NEUDA, M.D.
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In a previous paper1 I had reported that the sickle-inducing substance, the blood-group-enzyme (BGE), which was originally found in feces, was also present in the blood in certain diseases including sickle cell anemia. While, however, the BGE in feces is a normal constituent, the presence of this substance in the blood in disease is apparently an abnormal finding. In the presence of red cell sensitivity, for example, the BGE in blood might be a red cell damaging agent. This could possibly apply as an explanation to sickle cell anemia.
The BGE was, however, not only found in the blood of
NEUDA PM. RED BLOOD CELL SENSITIVITY IN CAUCASIANS*. Ann Intern Med. 1949;31:1024–1029. doi: https://doi.org/10.7326/0003-4819-31-6-1024
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Published: Ann Intern Med. 1949;31(6):1024-1029.
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