JOHN M. WELLER, M.D.; ISAAC M. TAYLOR, M.D.
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The demonstration in recent years that deficiency in intracellular potassium results in severe metabolic abnormalities, and that its repair is associated with a return to normal metabolic activity, has directed our attention to a study of factors which are responsible for the high intracellular-extracellular potassium gradient.
The basic problems of cellular potassium metabolism are immediately apparent if one considers the simple system of a human red cell suspended in plasma. The red cell contains nearly 150 mEq. of potassium per kilogram of water while the plasma contains less than 5 mEq. of potassium per kilogram of water. The questions which
WELLER JM, TAYLOR IM. SOME PROBLEMS OF POTASSIUM METABOLISM1. Ann Intern Med. ;33:607–612. doi: 10.7326/0003-4819-33-3-607
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Published: Ann Intern Med. 1950;33(3):607-612.
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