JOHN P. MERRILL, M.D.; HAROLD D. LEVINE, M.D., F.A.C.P.; WALTER SOMERVILLE, M.D., M.R.C.P.; STEPHEN SMITH 3rd, M.D.
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The toxicity to the living organism of an excess of potassium ion in the extracellular fluid has been recognized for many years.1, 2, 3 The accumulation of toxic amounts of potassium may occur by reason of: (1) excess intake,2, 4, 5 (2) faulty metabolic handling,6 and (3) decreased excretion of potassium liberated by catabolic processes.7, 8, 9 The syndrome is encountered most frequently in clinical practice as a consequence of impaired excretion of potassium in the presence of increased mobilization or intake.
The clinical syndrome of potassium intoxication has been recognized with increasing frequency10, 11, 12, 13, 14 and the
MERRILL JP, LEVINE HD, SOMERVILLE W, SMITH S. CLINICAL RECOGNITION AND TREATMENT OF ACUTE POTASSIUM INTOXICATION1. Ann Intern Med. ;33:797–830. doi: 10.7326/0003-4819-33-4-797
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Published: Ann Intern Med. 1950;33(4):797-830.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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