EMANUEL M. RAPPAPORT, M.D.; A. X. ROSSIEN, M.D.; LOUIS A. ROSENBLUM, M.D., F.A.C.P.
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The increased incidence of amebiasis in this country since the war has served to focus attention upon the extra-intestinal manifestations of this disease. These may be classified in two categories:
1. Symptoms due to hematogenous spread of the ameba.
2. Toxic symptoms arising from the primary intestinal focus.
In general the incidence of involvement of extra-intestinal organs is not directly related to the severity of the intestinal lesion. In fact, extra-intestinal symptoms frequently arise in the absence of intestinal symptoms. Furthermore, lesions in organs involved by the hematogenous route may flare up even following the cure of the primary intestinal
RAPPAPORT EM, ROSSIEN AX, ROSENBLUM LA. ARTHRITIS DUE TO INTESTINAL AMEBIASIS1. Ann Intern Med. ;34:1224–1231. doi: 10.7326/0003-4819-34-5-1224
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Published: Ann Intern Med. 1951;34(5):1224-1231.
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