HOWARD LACKAY; EDMUND L. HOUSEL, M.D.
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A serious and often fatal complication of auricular fibrillation, especially when associated with mitral stenosis, is the production of intraauricular thrombosis and embolism. When embolism is recurrent, the condition is likely to be fatal unless normal auricular contractions are restored and the source of emboli is thereby eliminated. Although restoration of normal rhythm by quinidine therapy has been recommended generally in the treatment of uncomplicated auricular fibrillation of short duration, there is a natural hesitation among many physicians to employ this drug in the presence of long established auricular fibrillation with repeated embolic episodes complicating serious heart disease because of
LACKAY H, HOUSEL EL. THE ARREST OF RECURRENT EMBOLISM DUE TO AURICULAR FIBRILLATION WITH MITRAL STENOSIS BY QUINIDINE-ANTICOAGULANT THERAPY1. Ann Intern Med. ;35:1143–1149. doi: 10.7326/0003-4819-35-5-1143
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Published: Ann Intern Med. 1951;35(5):1143-1149.
Cardiology, Rhythm Disorders and Devices.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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