Skip Navigation
Menu
Original Research |1 February 1952

THE ORAL ADMINISTRATION OF VITAMIN B12 IN TROPICAL SPRUE1

FEDERICO DIÉZ RIVAS, M.D.; RAMÓN M. SUÁREZ, M.D., F.A.C.P.; FEDERICO HERNÁNDEZ MORALES, M.D., F.A.C.P.; ENRIQUE PÉREZ SANTIAGO, M.D.

Article, Author, and Disclosure Information
Author, Article, and Disclosure Information
×
FULL TEXT

This content is PDF only. Please click on the PDF icon to access.

Abstract

Three years ago, Shorb1 discovered a new factor in refined liver extracts that was highly potent in promoting growth of the microörganism Lactobacillus lactis Dorner. Using the microbiologic method of Shorb, Riches2 et al. isolated a pure crystalline compound from liver and designated it vitamin B12. West3 proved that this substance possessed the property of inducing a hematopoietic response in patients with pernicious anemia in relapse. At about the same time, Smith4 in England announced the isolation of a factor apparently identical to vitamin B12.

CHEMISTRY OF VITAMIN B12

Crystalline vitamin B12 occurs as dark red needles. On a weight-for-weight

FULL TEXT
PDF
Not Available
Citations
Citation

RIVAS FD, SUÁREZ RM, MORALES FH, et al. THE ORAL ADMINISTRATION OF VITAMIN B12 IN TROPICAL SPRUE1. Ann Intern Med. 1952;36:583–591. doi: 10.7326/0003-4819-36-2-583

Download citation file:

© 2019

×
Permissions

Published: Ann Intern Med. 1952;36(2_Part_2):583-591.

DOI: 10.7326/0003-4819-36-2-583

6 Citations

Related Articles
THE ORAL USE OF COMBINED VITAMIN B12 AND FOLIC ACID IN TROPICAL SPRUE1
Annals of Internal Medicine; 36 (4): 1076-1085
Combined therapy with folic acid and vitamins B6 and B12 did not affect cancer risk in women at high risk for CV disease
Annals of Internal Medicine; 150 (6): JC3-9
Oral Administration of an Antibiotic (Norfloxacin) May Help Treat the Cardiac and Circulatory Complications of Liver Failure
Annals of Internal Medicine; 139 (3): I-62
Elevated Methylmalonic Acid and Total Homocysteine Levels Show High Prevalence of Vitamin B12 Deficiency after Gastric Surgery
Annals of Internal Medicine; 124 (5): 469-476
View MoreView Less

Journal Club
Combined therapy with folic acid and vitamins B6 and B12 did not affect cancer risk in women at high risk for CV disease
Annals of Internal Medicine; 150 (6): JC3-9
View MoreView Less

Related Topics
Celiac Disease and Malabsorption
Gastroenterology/Hepatology

Celiac Disease and Malabsorption, Gastroenterology/Hepatology.

PubMed Articles
Iron Support in Erythropoietin Treatment in Myelodysplastic Syndrome Patients Affected by Low-Risk Refractory Anaemia: Real-Life Evidence from an Italian Setting.
Acta Haematol 2019.
Botulinum Toxin Type A in Dental Medicine.
J Dent Res 2019.
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2019 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×