EVERETT H. SANNEMAN JR., M.D.; MARION F. BEARD, A.B., M.D., F.A.C.P.
This content is PDF only. Please click on the PDF icon to access.
The simultaneous discovery of vitamin B12 by Rickes and his co-workers1 and by Smith2 was soon followed by numerous clinical reports3, 4, 5, 6 of its efficacy in treating pernicious anemia in relapse. Many reports, particularly those of Ungley3 and Meacham et al.,9 suggested that it was equally effective as a maintenance therapy. Our group,7 however, has reported that in certain instances vitamin B12 alone is not a complete maintenance therapy, and the data suggested that some additional factor was necessary. Meyer10 has reported on the effectiveness of a combination of folic acid and vitamin B12 orally. Bethell11 and
SANNEMAN EH, BEARD MF. PARENTERAL B12-FOLIC ACID THERAPY IN PERNICIOUS ANEMIA*. Ann Intern Med. 1952;37:755–760. doi: https://doi.org/10.7326/0003-4819-37-4-755
Download citation file:
Published: Ann Intern Med. 1952;37(4):755-760.
Hematology/Oncology, Red Cell Disorders.
Copyright © 2020 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use