JOSEPH EARLE MOORE, M.D.; CHARLES F. MOHR, M.D., F.A.C.P.
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Present standard serologic tests for syphilis (hereafter abbreviated STS), routinely discovered in patients who have no history or physical evidence of that infection, may represent either latent syphilis, acquired or congenital, or biologic false-positive reactions (hereafter abbreviated BFP).
BFP reactors may be divided into two categories, acute and chronic.1 The acute reactions are due to a large number of infections, bacterial, viral, plasmodial, rickettsial or protozoal. They appear during or immediately after such a precipitating infectious cause, and regress spontaneously to normality within a brief period, not exceeding six months.
Chronic BFP reactors, on the other hand, are characterized by
MOORE JE, MOHR CF. THE INCIDENCE AND ETIOLOGIC BACKGROUND OF CHRONIC BIOLOGIC FALSE-POSITIVE REACTIONS IN SEROLOGIC TESTS FOR SYPHILIS: PRELIMINARY REPORT1. Ann Intern Med. ;37:1156–1161. doi: 10.7326/0003-4819-37-6-1156
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Published: Ann Intern Med. 1952;37(6):1156-1161.
Infectious Disease, Sexually Transmitted Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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