WILLIAM WEISS, M.D.
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Tuberculosis in the Negro race is more often acute and more often leads to death than in the white race. This is true even when environmental factors are similar in both races.1 Therefore, constitutional factors must be important in the Negro's reaction to tuberculous infection.
These constitutional factors are not easily defined and their influence is not readily measured in most cases. However, the sickling phenomenon, which is almost peculiar to the Negro, requires only a simple test to uncover its presence. Since blood supply is important in inflammatory diseases such as tuberculosis, it seems reasonable that sickling of red
WEISS W. THE THERAPEUTIC RESPONSE OF TUBERCULOUS NEGROES WITH THE SICKLE CELL TRAIT1. Ann Intern Med. 1953;38:523–527. doi: 10.7326/0003-4819-38-3-523
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Published: Ann Intern Med. 1953;38(3):523-527.
Hematology/Oncology, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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