STUART H. WALKER; ROBERT L. CAVENAUGH; HAROLD WILLIAMS
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With the availability of potent adrenal cortical replacement therapy, cortisone, and highly effective chemotherapeutic agents against the meningococcus, sulfadiazine and the broad spectrum antibiotics, a marked reduction in the mortality of the Waterhouse-Friderichsen syndrome was to be expected. However, it appears from the experience reported herein and that of others1 that we have but escaped the Scylla of fulminating peripheral vascular collapse to run upon the Charybdis of renal and myocardial insufficiency. Marangoni and D'Agati1 have emphasized the constant presence of renal insufficiency in the Waterhouse-Friderichsen syndrome, and demonstrated its second stage, prolonged anuria and azotemia following the resolution of
WALKER SH, CAVENAUGH RL, WILLIAMS H. THE PROLONGED WATERHOUSE-FRIDERICHSEN SYNDROME WITH RENAL AND MYOCARDIAL INSUFFICIENCY1. Ann Intern Med. ;38:610–619. doi: 10.7326/0003-4819-38-3-610
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© 2019
Published: Ann Intern Med. 1953;38(3):610-619.
DOI: 10.7326/0003-4819-38-3-610
Adrenal Disorders, Cardiology, CNS Infections, Endocrine and Metabolism, Infectious Disease.
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