MAURICE SOKOLOW, M.D., F.A.C.P.; MARY F. SCHOTTSTAEDT, M.D.
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Hypertension varies strikingly in its clinical course. One of the unexplained vagaries of this condition is the fact that in some instances the disease may be most benign, with little vascular deterioration for a period of 10 to 20 years, while in other cases such deterioration may occur within a few years. One variety of hypertensive disease has been singled out as being particularly ominous and has been designated as malignant, because the downward course is usually measured in months rather than in years. Occurrence of the malignant phase may be detected by the appearance of papilledema, although in
SOKOLOW M, SCHOTTSTAEDT MF. THE MANAGEMENT OF MALIGNANT HYPERTENSION*. Ann Intern Med. 1953;38:647–666. doi: https://doi.org/10.7326/0003-4819-38-4-647
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Published: Ann Intern Med. 1953;38(4):647-666.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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