MAXIMILIAN FABRYKANT, M.D.
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The brittle or labile diabetics pose a difficult problem even to physicians experienced in the treatment of diabetes. Such patients exhibit an extreme instability of their blood glucose regulation and, as previously shown,1 may be subject to pseudohypoglycemic reactions, that is, reactions which occur with normal or elevated blood glucose values and are refractory to carbohydrate administration. Inasmuch as most of our labile diabetics had electroencephalographic abnormalities that could not be ascribed to the immediate hypoglycemic effect of insulin or to diabetes per se, we have been led to the use of anticonvulsive drugs, which have proved highly effective in
FABRYKANT M. FURTHER STUDIES ON ELECTROCEREBRAL DYSFUNCTION AND THE USE OF ANTICONVULSANTS IN LABILE DIABETES1. Ann Intern Med. 1953;38:814–823. doi: 10.7326/0003-4819-38-4-814
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Published: Ann Intern Med. 1953;38(4):814-823.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism, Neurology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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