CARL W. TEMPEL; FORREST W. PITTS; WILLIAM E. DYE
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Six antimicrobial agents have been subjected to a methodical pattern of clinical investigation since 1946 at Fitzsimons Army Hospital. Approximately 1,300 patients have been evaluated under controlled conditions employing streptomycin, para-aminosalicylic acid, amithiozone, viomycin, terramycin and Isoniazid, either singly or in various combinations.1 Therapeutic efficacy, bacteriologic cultural and resistance studies, and toxicity formed the principal criteria for evaluating these drug regimens. Summary data on 875 patients observed on the research wards constitute the basis of this report.
Studies were performed on a homogeneous group of patients relative to extent and clinical pathologic type of disease. Almost all were young adult
TEMPEL CW, PITTS FW, DYE WE. ANTIMICROBIAL THERAPY OF PULMONARY TUBERCULOSIS: REVIEW OF SIX YEARS' EXPERIENCE AT FITZSIMONS ARMY HOSPITAL1. Ann Intern Med. ;39:61–73. doi: 10.7326/0003-4819-39-1-61
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Published: Ann Intern Med. 1953;39(1):61-73.
Hospital Medicine, Infectious Disease, Mycobacterial Infections, Pulmonary Tuberculosis, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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