JAMES TOMPKINS, M.D.; IRWIN M. WEINSTEIN, M.D.
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Lipoid proteinosis is a peculiar abnormality of fat deposition characterized by the appearance of white or yellow plaques and nodules in the skin and mucous membranes, producing hoarseness due to vocal cord involvement, sometimes associated with diabetes mellitus, a history of consanguinity in the parentage and familial occurrence. The disease is quite rare, only 34 cases having been reported in the literature to date. The course is apparently benign unless respiratory difficulty ensues. Wiethe1 published the first notable description of this condition in 1924, but Urbach2 deserves credit for recognizing the nature of the disease and for coining the name
TOMPKINS J, WEINSTEIN IM. LIPOID PROTEINOSIS: TWO CASE REPORTS INCLUDING LIVER BIOPSIES, SPECIAL BLOOD LIPID ANALYSES, AND TREATMENT WITH A LIPOTROPIC AGENT1. Ann Intern Med. ;41:163–171. doi: 10.7326/0003-4819-41-1-163
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Published: Ann Intern Med. 1954;41(1):163-171.
Cardiology, Coronary Risk Factors, Dyslipidemia.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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