EDWARD C. HEYDE, M.D.
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Hereditary hemorrhagic telangiectasia is one form of capillary heredopathia distinguished by the familial incidence of dilated small blood vessels histologically comprising a single layer of endothelium, with a conspicuous deficiency of muscular and elastic layers of the vessel walls.1 The lesions are true vascular "spiders," such as one sees in pregnancy2 and in acute or chronic liver disease. They occur most commonly on the oral and nasal mucosa, lips, face, arms and upper trunk, but may also be located in the viscera or, indeed, anywhere in the body. The association of pulmonary arteriovenous aneurysms (fistulae) with this disease has been
HEYDE EC. HEREDITARY HEMORRHAGIC TELANGIECTASIA: A REPORT OF PULMONARY ARTERIOVENOUS FISTULAE IN MOTHER AND SON; MEDICAL (HORMONAL) AND SURGICAL THERAPY OF THIS DISEASE1. Ann Intern Med. 1954;41:1042–1053. doi: 10.7326/0003-4819-41-5-1042
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Published: Ann Intern Med. 1954;41(5):1042-1053.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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