WILLIAM WEINGARTEN, M.D.; GLENN GORDON, M.D.
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The diagnosis of thymoma can present much difficulty because of the unusual location, slow growth and lack of classic signs and symptoms.
The thymus usually undergoes gradual regression at adolescence but may persist beyond puberty and produce no symptoms. When the thymus does not regress it may compress mediastinal structures, undergo malignant change or give rise to myasthenia gravis.
Weigert1 in 1901 first reported a case of myasthenia gravis associated with a thymoma. Since then, many reports confirming Weigert's findings have appeared in the medical literature. Seybold et al.2 have found that 75.6% of their patients with myasthenia gravis had
WEINGARTEN W, GORDON G. THYMOMA: DIAGNOSIS AND TREATMENT1. Ann Intern Med. 1955;42:283–295. doi: 10.7326/0003-4819-42-2-283
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Published: Ann Intern Med. 1955;42(2):283-295.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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