W. B. SPAULDING, M.D., F.R.C.P. (C.); W. A. OILLE, M.D., F.R.C.P. (C.); A. G. GORNALL, Ph.D.
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A few patients with Cushing's syndrome have severe electrolyte disturbances in the form of hypokalemia, hypochloremia, alkalosis and hyperglycemia.1, 2 We are reporting a patient who lacked most of the features of Cushing's syndrome but in whom this type of biochemical disorder prompted an investigation of the adrenals and revealed an unusual group of findings. The urinary corticoid output was increased. Pyelography showed an adrenal tumor, but the tumor removed surgically proved to be metastatic and autopsy showed the tumor to have originated in the lung.
The patient was a 56 year old office worker who had been
SPAULDING WB, OILLE WA, GORNALL AG. MINERALOCORTICOID-LIKE DISTURBANCE ASSOCIATED WITH ADRENAL METASTASES FROM A BRONCHOGENIC CARCINOMA*. Ann Intern Med. 1955;42:444–451. doi: https://doi.org/10.7326/0003-4819-42-2-444
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Published: Ann Intern Med. 1955;42(2):444-451.
Adrenal Disorders, Endocrine and Metabolism, Endocrine Cancer, Hematology/Oncology, Lung Cancer.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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