WARREN D. PLATT JR., M.D.; IRVING H. STEINBERG, M.D.
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An approach to the therapy of rheumatoid arthritis through treatment of the associated vascular disturbance has been used by many investigators, with inconsistent results. In 1930 a most direct and apparently successful approach was used by Rowntree et al.1 in the performance of lumbar and cervicothoracic sympathectomies in 17 patients with rheumatoid arthritis. The rationale for such treatment lay in the frequently noted vegetative disturbances of abnormal sweating, cyanosis, coldness and tingling in the extremities of patients suffering from rheumatoid arthritis. The results of sympathectomy indicated that there was marked relief of periarticular pain in 12 of the 17 patients
PLATT WD, STEINBERG IH. THE TREATMENT OF RHEUMATOID ARTHRITIS WITH HEXAMETHONIUM CHLORIDE: A PRELIMINARY REPORT1. Ann Intern Med. ;42:816–825. doi: 10.7326/0003-4819-42-4-816
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Published: Ann Intern Med. 1955;42(4):816-825.
Rheumatoid Arthritis, Rheumatology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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