W. J. SAYER; G. ENTWHISLE; B. UYENO; R. C. BIGNALL
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Epidemic hemorrhagic fever (EHF) is an infectious disease of unknown etiology which was first encountered by the U. S. Army in Korea during the spring of 1951. It is characterized by an initial toxic-febrile state with spontaneous petechiae, leukocytosis and thrombocytopenia, followed by variable degrees of renal and cardiovascular involvement. As yet, no specific therapeutic agent has been found for this disease.
A nonspecific beneficial effect from the administration of cortisone in conjunction with the appropriate antibiotic preparation, has been demonstrated in patients ill with typhoid fever,1 scrub typhus2 and Rocky Mountain spotted fever.3 For these patients the toxic-febrile
SAYER WJ, ENTWHISLE G, UYENO B, et al. CORTISONE THERAPY OF EARLY EPIDEMIC HEMORRHAGIC FEVER: A PRELIMINARY REPORT*. Ann Intern Med. 1955;42:839–851. doi: https://doi.org/10.7326/0003-4819-42-4-839
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Published: Ann Intern Med. 1955;42(4):839-851.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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