JOHN H. CHILDERS, M.D.; JOHN W. MIDDLETON, M.D., F.A.C.P.; MARTIN SCHNEIDER, M.D.
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Eosinophilic granuloma of bone was described by Otoni and Ehrlich1 in 1940 and was referred to as "solitary granuloma of bone simulating primary neoplasm." Lichtenstein and Jaffe2 described this entity practically simultaneously, and first applied the term "eosinophilic granuloma." Farber,3 Green and Farber4 and Mallory5 pointed out that solitary or eosinophilic granuloma of bone was but one of related disorders referred to as Hand-Schüller-Christian and Letterer-Siwe disease. The differential features of these lesions depend largely upon the tissues involved.
Currens6 recorded a case of Hand-Schüller-Christian disease with a defect in the right parietal region of the skull and with radiologic
CHILDERS JH, MIDDLETON JW, SCHNEIDER M. EOSINOPHILIC GRANULOMA OF FEMUR AND LUNGS: A CASE REPORT1. Ann Intern Med. 1955;42:1297–1308. doi: 10.7326/0003-4819-42-6-1297
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Published: Ann Intern Med. 1955;42(6):1297-1308.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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