MAURICE H. LASZLO, M.D.; ARTURO ALVAREZ, M.D.; FREDERIC FELDMAN, M.D.
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The first description of a case of thrombotic thrombocytopenic purpura was given in 1925 by Moschcowitz,1 who reported a case of acute febrile hemolytic anemia with petechiae and the development of neurologic signs shortly before death. Microscopic examination showed hyaline thrombi in terminal arterioles and capillaries. In 1936 Baehr et al.2 reported four cases. They believed that the thrombi were composed of platelets. Since then more than 40 case reports have appeared in the literature. An excellent review of the literature has recently been presented by Barondess.3 The syndrome has been clearly characterized by the clinical triad of hemolytic anemia,
LASZLO MH, ALVAREZ A, FELDMAN F. THE ASSOCIATION OF THROMBOTIC THROMBOCYTOPENIC PURPURA AND DISSEMINATED LUPUS ERYTHEMATOSUS: REPORT OF A CASE1. Ann Intern Med. ;42:1308–1320. doi: 10.7326/0003-4819-42-6-1308
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Published: Ann Intern Med. 1955;42(6):1308-1320.
Lupus Erythematosus, Rheumatology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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