ALAN N. MORRISON, M.D.; MONTAGUE LANE, M.D.
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Since the original description of this disease in 1882, reports of approximately 280 cases have appeared in the literature. The condition was originally considered to be a primary splenic epithelioma,1 and it was Gaucher who first described the cells in the spleen characteristic of this disease. The involvement of the liver by these cells was observed by Bovaird2 in 1900. The classic features of Gaucher's disease—hepatosplenomegaly, brownish pigmentation of the skin, pingueculae, bone marrow infiltration with resulting anemia, leukopenia, thrombocytopenia, osseous changes, and central nervous system manifestations in infants—are well known. Despite the frequent involvement of the liver, aberrations in
MORRISON AN, LANE M. GAUCHER'S DISEASE WITH ASCITES: A CASE REPORT WITH AUTOPSY FINDINGS1. Ann Intern Med. 1955;42:1321–1329. doi: 10.7326/0003-4819-42-6-1321
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Published: Ann Intern Med. 1955;42(6):1321-1329.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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