ISRAEL STEINBERG, M.D., F.A.C.P.; WILLIAM GELLER, M.D.
Arachnodactyly (Marfan's syndrome) is a rare hereditary disease of unknown etiology. It is characterized by widespread malformations of the skeletal, cardiovascular and ophthalmic systems. Marfan in 18961 described the first case and called attention to the long, thin, spider-like appearance of the extended extremities. Soon arachnodactyly2 became established as the name of the disorder.
The association of cardiovascular anomalies with arachnodactyly became evident with complete autopsies. Forty-one necropsies of Marfan's disease have been reported; eight were under 28 months of age and had no aortic lesions; the remaining 33 were adults (14 to 55 years); all had lesions of the
STEINBERG I, GELLER W. ANEURYSMAL DILATATION OF AORTIC SINUSES IN ARACHNODACTYLY: DIAGNOSIS DURING LIFE IN THREE CASES1. Ann Intern Med. 1955;43:120–132. doi: 10.7326/0003-4819-43-1-120
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Published: Ann Intern Med. 1955;43(1):120-132.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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