THOMAS N. JAMES, M.D.; HENRY W. POST, M.D.; F. JANNEY SMITH, M.D., F.A.C.P.
Even more striking than the relative rarity of coronary thrombosis in women in the reproductive phase of life is the fact that thrombosis is seldom due to spontaneous arteriosclerosis. The unusual facets of myocardial infarction in women have evoked a number of interesting observations on the sexual aspects of this disease. Dock1 demonstrated a remarkably thinner intima of the coronary arteries in females even in infancy. Wuest, Dry and Edwards2 carefully examined the coronary arteries of bilaterally oophorectomized women and found they had a greater amount of atherosclerosis than a control group. Barr3 was able to lower the cholesterol/phospholipid ratio
JAMES TN, POST HW, SMITH FJ. MYOCARDIAL INFARCTION IN WOMEN*. Ann Intern Med. 1955;43:153–164. doi: https://doi.org/10.7326/0003-4819-43-1-153
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Published: Ann Intern Med. 1955;43(1):153-164.
Acute Coronary Syndromes, Cardiology, Coronary Heart Disease, Emergency Medicine.
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