Skip Navigation
Menu
Original Research |1 August 1955

SERUM GLUTAMIC OXALACETIC TRANSAMINASE ACTIVITY AS AN INDEX OF LIVER CELL INJURY: A PRELIMINARY REPORT12

FELIX WRÓBLEWSKI, M.D.; JOHN S. LADUE, M.D., Ph.D., F.A.C.P.

FULL TEXT

Abstract

INTRODUCTION

Glutamic oxalacetic transaminase is widely distributed in animal tissues. Its greatest concentration, however, is in heart muscle, skeletal muscle, brain, liver and kidney, in decreasing order.1 We have already shown that, when measured in serum, this enzyme is elevated after acute myocardial infarction.2 This finding led us to study its concentration in liver diseases, since the enzyme is present in relatively high concentration in liver.

Glutamic oxalacetic transaminase is present in all human sera and will henceforth be referred to as SGO-T. Comparable concentrations are found whether chromatographic or spectrophotometric methods are employed.3 When serum is added to excesses

FULL TEXT
PDF
Not Available
Citations
Citation

WRÓBLEWSKI F, LADUE JS. SERUM GLUTAMIC OXALACETIC TRANSAMINASE ACTIVITY AS AN INDEX OF LIVER CELL INJURY: A PRELIMINARY REPORT12. Ann Intern Med. 1955;43:345–360. doi: 10.7326/0003-4819-43-2-345

Download citation file:

© 2019

×
Permissions

Published: Ann Intern Med. 1955;43(2):345-360.

DOI: 10.7326/0003-4819-43-2-345

293 Citations

Related Articles
SERUM GLUTAMIC-OXALACETIC TRANSAMINASE ACTIVITY IN CONDITIONS ASSOCIATED WITH MYOCARDIAL INFARCTION. I. BODILY TRAUMA1
Annals of Internal Medicine; 46 (3): 485-496
SERUM GLUTAMIC OXALACETIC TRANSAMINASE LEVELS IN 266 SURGICAL PATIENTS1
Annals of Internal Medicine; 52 (6): 1279-1288
SERUM GLUTAMIC OXALACETIC TRANSAMINASE (SGO-T) IN CONGESTIVE HEART FAILURE: CLINICAL STUDY AND REVIEW OF THE LITERATURE1
Annals of Internal Medicine; 52 (5): 1042-1050
SERUM TRANSAMINASE IN PULMONARY DISEASE AND MULTIPLE INFARCTIONS1
Annals of Internal Medicine; 46 (6): 1105-1112
View MoreView Less

Journal Club
Tranexamic acid reduced mortality in trauma patients who were bleeding or at risk for bleeding
Annals of Internal Medicine; 159 (6): JC3
An 8-factor prognostic model predicted early death in patients with traumatic bleeding
Annals of Internal Medicine; 157 (10): JC5-13
Early treatment with tranexamic acid reduced bleeding death in patients with clinically important hemorrhage due to trauma
Annals of Internal Medicine; 155 (2): JC1-4
The Canadian C-Spine Rule, used by nurses, accurately identified cervical-spine injury in patients with trauma
Annals of Internal Medicine; 154 (2): JC1-13
View MoreView Less

Related Topics
Emergency Medicine

Emergency Medicine.

PubMed Articles
Convergence of three parcellation approaches demonstrating cerebellar lobule volume deficits in Alcohol Use Disorder.
Neuroimage Clin 2019;
The association of angiopoietin-like peptide 4 levels with obesity and hepatosteatosis in adolescents.
Cytokine 2019;
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2019 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×